Treatment of Corneal Infection with Ps. Pyocyanea by Subconjunctival Injection of Polymyxin E

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Treatment of corneal infection with ps. pyocyanea by subconjunctival injection of polymyxin E.

THE properties of polymyxin in relation to ocular therapeutics have recently been discussed at some length ; the penetration of this antibiotic into the eye of the rabbit after subconjunctival injection was estimated and the results obtained in the treatment of corneal infection experimentally produced with Ps. pyocyanea have been reported (Ainslie and Smith, 1951). It is well known that this t...

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CORNEAL ULCERATION WITH Ps. PYOCYANEA.

DEAR SIRS-Two recent articles by Klein and Millwood (1952, 1953) have prompted me to make a few comments on some eight cases of corneal ulceration with the Ps. pyocyanea which I have seen since an article by Bignell appeared in 1951. Of the eight cases, six had a simple corneal foreign body removed, and in these the cornea became infiltrated round the former site of the foreign body within 48 h...

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Polymyxin E, penetration into the eye and therapeutic value in experimental infection due to Ps. pyocyanea.

THE polymyxins are a group of five closely allied antibiotics extracted from the Bacillus polymyxa. In vitro and in the field of general medicine they have been found bactericidal to nearly all Gram-negative bacilli, and the good results obtained in combating Ps. pyocyanea infection of burns by the local application of polymyxin (Jackson and others, 1951) suggested the possibility of using them...

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Chloramphenicol applied in calcium alginate caps for the control of experimental corneal infection with Ps. pyocyanea.

(i) ease of penetration into the ocular tissues, (ii) toxicity for ocular tissues, (iii) effectiveness against standard experimental ocular infections, (iv) effectiveness against clinical ocular infections. The penetration of chloramphenicol was investigated by Leopold, Nichols, and Vogel (1950), who found that by using it as eyedrops in aqueous solution or in propylene glycol, or as an eye oin...

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Control of experimental corneal infection with medicated semi-solid contact cap and disk; infection with Ps. pyocyanea treated with streptomycin.

MULES (1894) wrote that where " the action of micro-organisms on an abraded surface may cause or is causing destructive changes " the indications would be to remove the irritating elements and allow the natural process of repair to heal the breach of surface ". He sought to achieve this by placing a gelatine wafer impregnated with iodoform on the corneal surface and keeping the eye bandaged. He...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1953

ISSN: 0007-1161

DOI: 10.1136/bjo.37.6.336